Beschreibung
454 Life Sciences, a center of excellence of Roche Applied Science, develops and commercializes the innovative GS Junior and GS FLX Systems for high-throughput DNA sequencing. Specific applications include de novo sequencing and resequencing of whole genomes, targeted resequencing of genomic regions of interest, metagenomics, transcriptome sequencing and methylation analysis. The hallmark of 454 Sequencing Systems are the long, highly accurate sequence reads, including paired end reads. The technology has enabled over 1,000 peer-reviewed publications in diverse research fields such as cancer, infectious disease, immunogenetics, drug discovery, agriculture, environmental ecology, paleontology and many more.